Tirzepatide and Semaglutide are both GLP-1 receptor agonists. Tirzepatide is different in that it is also a GIP receptor agonist. Here’s what this difference means for you:
WEIGHT LOSS
In clinical trials, the following results were recorded:
SIDE EFFECTS
Over a study of more than 22 clinical trials, the following side effects were reported:
Side Effects: Semaglutide vs Tirzepatide
| Semaglutide | Tirzepatide | Placebo | |
|---|---|---|---|
| Nausea | 16-20% | 25-28% | 6-8% |
| Diarrhea | 9% | 19-23% | 2-8% |
| Vomiting | 5-9% | 8-13% | 2% |
| Belching | No Data | 4-5% | 1% |
| Constipation | 3-5% | 11-17% | 2-5% |
| Stomach Pain | 6-7% | 9-10% | 5% |
| Heartburn | 3-4% | 9-10% | 2-4% |
| GERD | No Data | 4-5% | 2% |
COST
When purhasing through Hydrations Wellness
| Semaglutide (2.4mg) | Tirzepatide (15mg) | |
|---|---|---|
| 1 YR | $2899 | $4679 |
Ultimately, if weight loss is your main goal (and you are not limited by budget) and are not the type to typically have side effects when you take medications, then Tirzepatide is probably the best fit for you. Otherwise, Semaglutide will most likely be your best option from a cost and side effect perspective.
